You’re Doing Everything Right. So Why Isn’t the Scale Moving?
Eating well and exercising, but still not losing weight? Endocrinologist Dr. Maha Abboud explains the hidden medical causes she looks for first.

You have cut back on what you eat, you have been showing up for your workouts, and you have followed the advice you were given as carefully as anyone could. And still, week after week, the number on the scale barely moves. If that sounds familiar, I want you to know that I hear some version of this story in my office almost every week, and it is one of the most discouraging things a patient can describe to me.
After 30 years of practicing endocrinology, I have learned that weight loss is rarely as simple as eating less and moving more. Those habits matter, and I will never tell a patient to stop taking care of themselves. But when someone is doing the work and getting nothing back, the more useful question is what else is happening inside their body, and most of the people I see have never had that question properly answered.
Why “eat less, move more” stops working
Your body is designed to protect the weight it already has. When you eat less, it responds by lowering the amount of energy it burns at rest and by turning up the hormones that make you hungry. This is called metabolic adaptation, and it is one of the main reasons that a diet which worked well in the first few weeks seems to stop working later.
One of the clearest examples comes from a National Institutes of Health study of former contestants on the television show The Biggest Loser. Six years after the competition, researchers found that the contestants' resting metabolism was still about 500 calories a day lower than would be expected for people of their size. Their bodies were still pushing back years after the dieting had ended.
I share this with my patients because it explains so much of the frustration they feel. When you eat carefully and see little change, it is easy to conclude that you must be doing something wrong. Very often, your body is simply doing what it was built to do. And that is in a person with no underlying medical problem. When a hormonal or metabolic condition is also involved, losing weight can become much harder, and no amount of extra effort will fully overcome it until the condition itself is found and treated.
What may be standing in your way
These are the factors I look for most often when a patient tells me the scale will not move. Many people have more than one, and several of them cause no obvious symptoms, which is why they are so easily missed.
Insulin resistance
Insulin is the hormone that moves sugar from your blood into your cells. When your cells stop responding to it well, your body makes more and more insulin to compensate, and high insulin levels make it easier for your body to store fat and harder to use it. According to the National Institute of Diabetes and Digestive and Kidney Diseases, insulin resistance usually causes no symptoms at all, so many people have it for years without knowing. It is also the step before prediabetes and type 2 diabetes, which means finding it early protects far more than your weight.
Thyroid disorders
Your thyroid sets the pace of your metabolism, so when it is underactive, your body burns less energy and you may feel tired, cold, and sluggish. I want to be honest with you here, because the thyroid is often blamed for more than it causes. The American Thyroid Association notes that the weight gained from an underactive thyroid is usually around 5 to 10 pounds, much of it salt and water. Treating the thyroid properly matters a great deal for how you feel and for your long-term health, but if it is the only thing we look at, we may miss the larger cause.
Polycystic ovary syndrome (now called PMOS)
Polycystic ovary syndrome, which was officially renamed polyendocrine metabolic ovarian syndrome (PMOS) in May 2026 to better reflect that it is a hormonal and metabolic condition, is far more common than most women realize. The World Health Organization estimates that it affects 10 to 13 percent of women of reproductive age, and that up to 70 percent of those women have never been diagnosed. Insulin resistance affects the large majority of women with the condition, including many who are not overweight, and it often shows up as weight gain around the belly that does not respond to dieting. Irregular periods, acne, and unwanted hair growth are other clues.
Iron and vitamin deficiencies
Low iron is common in women under 50, especially those with heavy periods. The National Institutes of Health lists tiredness, weakness, and a reduced ability to exercise among its symptoms. A deficiency like this may not add pounds directly, but it can leave you too exhausted to keep up the activity you are working so hard to maintain.
Medications
Some very common prescriptions can cause weight gain or make it harder to lose. The Endocrine Society’s guidelines on obesity treatment include certain antidepressants, antipsychotics, seizure medications, steroids such as prednisone, beta-blockers for blood pressure, and some diabetes medications. If you take one of these, please do not stop it on your own. Often, there is an alternative that is kinder to your weight, and it is worth a conversation with your doctor.
Sleep and stress
In a study at the University of Chicago, just two nights of short sleep raised levels of ghrelin, the hormone that drives hunger, by 28 percent and increased hunger by 24 percent, with the strongest cravings for high-calorie, high-carbohydrate foods. Chronic stress works in a similar way through the hormone cortisol.
Cortisol problems
Cortisol is the hormone your body releases in response to stress, and when it stays too high for too long, it can cause weight gain, particularly around the face and the middle of the body, that does not respond to dieting. This is one of the conditions I look for most carefully, because it is so easy to miss. Your body does not release cortisol at a steady rate. The levels rise and fall throughout the day, so a single blood test taken at one moment can come back normal even when there is a real problem. For that reason, I often use tests that capture more of the day, such as a 24-hour urine collection or a late-night saliva sample, which the Endocrine Society recommends over a random blood test. And when the results come back normal but your symptoms still point in that direction, I do not give up. We keep investigating until we have an answer.
One patient’s story
I think often of one patient who came to me after her weight had started climbing suddenly, with no change in how she was eating or how active she was. She had already tried everything she could think of, and nothing was working. By the time she reached my office, she was frustrated and starting to believe the problem was her own lack of willpower. On the surface, nothing obvious stood out, but her story did not fit, so we investigated more deeply. Sure enough, the cause turned out to be a problem with her cortisol. Her own hormones were pushing her body to gain weight, and no diet could have fixed that. Once we understood what was happening, we finally had something real to treat, and she finally had an explanation that made sense. I am happy to say she is doing well today.
Finding the missing piece of your puzzle
At Qua Wellness and Med Spa, we specialize in finding the missing piece of your puzzle. I see every patient myself, and as a triple board-certified endocrinologist, I approach weight the way I approach any hormonal problem, by looking for the cause before deciding on the treatment.
During your initial evaluation, we look beyond calories and exercise. We take time to understand your history, including what you have tried, what your weight has done over the years, the medications you take, how you sleep, and how your energy and cycles have changed. Then we investigate the underlying factors that are so often missed, including hormonal imbalances, insulin resistance, thyroid disorders, iron or vitamin deficiencies, medication effects, and other metabolic conditions. Many doctors rely on the same routine blood tests for every patient, but I choose the tests based on what your history and symptoms tell me, so no two evaluations look exactly the same, and we take whatever time your situation needs. At your visits, I also use a specialized scale that tells me much more than your weight, and it helps guide me when a slow metabolism may be part of the picture.
Sometimes the answer has less to do with trying harder and more to do with asking the right questions and finding the right answers. When we identify what is holding you back, we can create a personalized treatment plan to help you move forward.
What I want every patient to leave with is a clear explanation of what is happening in their body and a plan that makes sense for their life. For many of the people I see, that explanation is the first time anyone has taken their struggle seriously.
Where to go from here
Over the coming weeks, I will be sharing real patient transformation stories in a short video series. In each one, you will hear what was standing in that person’s way, what we uncovered together, and how their life changed once we knew. I hope that in at least one of them, you recognize a little of your own story. You can follow along on Instagram @quawellnessandmedspa, where every transformation has its own story to tell.
If you have been doing everything right and still feel stuck, your struggle deserves a real answer, and I would be glad to help you find it. You can request an appointment at our Burr Ridge clinic 630-561-0590 or book directly here.
Qua Wellness and Med Spa. Feel Good. Look Good. Be Good?
Information in this article is general and is not medical advice. Individual results vary.